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| Eating 30 grams of soy protein every day is beneficial for intestinal and muscle health! |
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| Ya Dou Dou News [2026/5/23] |
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Recently, the international authoritative journal "Journal of Cachexia, Sarcopenia and Muscle" published the heavyweight research results of Sun Jianqin's team at East China Hospital. The study confirmed through clinical trials that daily intake of 30 grams of soy protein can effectively improve muscle health; The key to its effectiveness lies in the dietary supplementation of soy protein, which can reconstruct the structure of intestinal microbiota, promote the proliferation of beneficial bacteria, inhibit the growth of harmful bacteria, enrich nutrient synthesis pathways, downregulate inflammatory pathways, and increase the levels of beneficial metabolites such as short chain fatty acids, thereby reducing systemic inflammation, maintaining muscle mass, and improving muscle movement function.
This study conducted a 12 week single center randomized controlled trial on 84 elderly individuals residing in nursing facilities, with 53 participants providing fecal samples included in the core analysis. In the experiment, the intervention group of elderly people supplemented 10 grams of soy protein three times a day, totaling 30 grams per day, while the control group maintained a regular diet. Researchers collected fecal samples from subjects at different stages of the experiment, analyzed gut microbiota composition, measured short chain fatty acid concentrations, and evaluated muscle function indicators such as calf circumference and 6-meter walking time. The results showed that the calf circumference of the intervention group slightly increased by 0.56 ± 0.22 cm, while the control group significantly decreased by 0.91 ± 0.26 cm. In addition, the 6-meter walking time of the intervention group showed an improvement trend, and systemic inflammation indicators were also significantly reduced. The study also found that the core function of soy protein is to regulate gut microbiota and reshape metabolic pathways. The intervention group showed a significant increase in the abundance of beneficial bacteria producing short chain fatty acids in the gut, a significant decrease in harmful bacteria, enrichment of pathways such as glutamate anaerobic degradation and vitamin biosynthesis, and a significant decrease in pro-inflammatory pathway activity. The increase in the concentration of short chain fatty acids in feces has become a key link between gut microbiota and muscle health, and its content is positively correlated with the muscle movement ability and body mass status of elderly people. This study not only provides a safe and convenient dietary intervention plan for the prevention and treatment of sarcopenia in the elderly worldwide, but also provides key clinical evidence for the "gut muscle axis" theory, filling the research gap in the role and mechanism of nutritional intervention in improving sarcopenia.
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